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TAmiRNA > products > thrombomiRTM
thrombomiR - biomarkers of platelet function

thrombomiRTM

microRNA qPCR workflow

 

Platelet microRNAs (thrombomiRs) are novel biomarkers for platelet function and can be detected in plasma or serum due to secretion from platelets upon their activation. This review, published by our scientific partners, gives detailed insight into the clinical utility of platelet microRNAs as in vivo biomarkers of platelet function.

The thrombomiRTM kit is the only standardized qPCR kit that enables its users to:

  • quantify 10 platelet microRNAs in <200 µL plasma or serum (human, mouse and rat) 
  • work with frozen sample material after several years of storage
  • take advantage of an optimized quality control design and tailor-made software
  • have a simple one-stop solution for in-house platelet microRNA analysis

 

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Table 1: list of thrombomiRs
Table 1: list of thrombomiRs
Figure 1: thrombomiRs - mode of action
Figure 1: thrombomiRs - mode of action

Highlights

ThrombomiRs are platelet microRNAs that have been carefully selected for this kit based on a series of prospective and cross-sectional studies. Results obtained with the thrombomiRTM kit can be used by researchers and clinicans to:

  • gain insights into the molecular function of platelets in vivo
  • determine the effect of a treatment on platelet reactivity in vivo
  • diagnose platelet-related disorders
  • study the utility of platelet microRNAs as risk factors for cardiovascular and metabolic diseases 

 

Commonly used platelet function tests e.g. LTA, VerifyNow® or PFA-100® , require fresh blood and agonists; therefore, they clearly lack standardization and their analytical variability may induce misinterpretations.

The thrombomiRTM kit enables an in vivo measure of platelet function, independently of the activation pathway (Figure 1).

 

we test your sample with our thrombomiRTM kit - more about this service

 

productportfolio

product name required components description price information
KT-021-TR
thrombomiRTM kit 		miRCURYTM RNA Isolation Kit
ExiLENT SYBR® Green Master Mix
thrombomiRTM kit		 analysis of 16 microRNAs
48 plasma samples		 EURO 4989.- product sheet
manual
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KT-022-TR
thrombomiRTM
custom kit
miRCURYTM RNA Isolation Kit
ExiLENT SYBR® Green Master Mix
thrombomiRTM custom kit		 custom plate design inquire inquire