4 12, 2025

Synovial Fluid and Serum microRNA Signatures in Equine Osteoarthritis

2025-12-04T11:05:09+01:00December 4th, 2025|biomarker, Illumina NewSeq2000, microRNA, microRNA services, miND, miND spike ins, miND spike-in, NGS, Osteoarthritis, quality, Synovial fluid|0 Comments

New research highlights the potential of circulating miRNAs as biomarkers for joint degeneration A new peer-reviewed study has been published in the International Journal of Molecular Sciences (IJMS): “Synovial Fluid and Serum MicroRNA Signatures in Equine Osteoarthritis.” This work provides important insights into how microRNAs (miRNAs) in serum and synovial fluid reflect the presence of osteoarthritis (OA) in horses. 🎯 Study Aim The researchers sought to identify disease-associated miRNAs that differ between healthy horses and horses with osteoarthritis. Their goal was to uncover molecular signatures that could support the development of novel biomarkers for early detection and monitoring of OA. 🔬 Methods Serum and synovial fluid samples were collected from healthy controls (n = 4) and horses [...]

26 11, 2025

TAmiRNA and Orthopaedic Hospital Speising Publish Landmark Data on promiR® for Accurate Diagnosis of Periprosthetic Joint Infections

2025-12-04T11:05:55+01:00November 26th, 2025|biomarkers in orthopaedics, Illumina NewSeq2000, microRNA, microRNA services, miND, miND spike ins, miND spike-in, NGS, periprosthetic joint infections, promiR, quality, Synovial fluid|Comments Off on TAmiRNA and Orthopaedic Hospital Speising Publish Landmark Data on promiR® for Accurate Diagnosis of Periprosthetic Joint Infections

On November 19th, 2025, the study “Synovial Fluid MicroRNA Biomarkers Enable Accurate Diagnosis of Hip and Knee Periprosthetic Joint Infections” by Frank et al. was published in the Journal of Bone and Joint Surgery. This peer-reviewed publication marks an important milestone in TAmiRNA’s biomarker development program and presents promiR®, our novel microRNA-based diagnostic panel designed to improve the pre-operative assessment of periprosthetic joint infections (PJIs). Clinical Challenge PJIs remain one of the most serious and difficult complications following total joint replacement. Current diagnostic methods—including inflammatory markers, imaging, and cultures—often lack sensitivity and specificity, especially for low-grade or culture-negative infections. Even advanced approaches such as PCR or next-generation sequencing can suffer from contamination risks and ambiguous [...]

22 09, 2025

TAmiRNA @ GSEV 2025

2025-09-22T08:52:59+02:00September 22nd, 2025|biomarker, Biomarker Discovery, biomarkers, microRNAs, NGS, periprosthetic joint infections, small RNA-sequencing, Synovial fluid|Comments Off on TAmiRNA @ GSEV 2025

TAmiRNA Announces Gold Sponsorship of GSEV Autumn Meeting 2025 and Presentation by Matthias Hackl TAmiRNA, a pioneer in transcriptomics-based biomarker research, is proud to announce its participation as a Gold Sponsor at the GSEV Autumn Meeting 2025, hosted by the German Society for Extracellular Vesicles (GSEV). The annual conference will take place on September 25–26, 2025, at the Audimax of the University Hospital Essen. As part of the scientific program, Matthias Hackl (TAmiRNA) will deliver a presentation on Thursday, September 25, at 12:15 pm entitled: “Small RNA-sequencing (miND®) Enables Discovery of EV-specific MicroRNA Signatures to Support EV Therapeutics Development.” “Using miND®, we can robustly identify EV-specific microRNA signatures – a critical step toward enabling data-driven research and [...]

8 09, 2025

TAmiRNA @ EBJIS 2025

2025-09-17T11:35:44+02:00September 8th, 2025|biomarker, Biomarker Discovery, biomarkers, microRNAs, NGS, periprosthetic joint infections, small RNA-sequencing, Synovial fluid|Comments Off on TAmiRNA @ EBJIS 2025

TAmiRNA is proud to announce its participation at the upcoming European Bone and Joint Infection Society (EBJIS) Meeting 2025 in Ferrara, Italy. On Thursday, September 11, 2025 at 11:00 (Sala Emilia), Dr. Bernhard JH Frank will present groundbreaking new results from a collaborative study conducted with the Orthopaedic Hospital Speising and Dr. Jochen G. Hofstätter. The presentation is entitled: “Synovial fluid microRNA biomarkers enable accurate diagnosis of hip and knee periprosthetic joint infections.” Synovial fluid microRNA biomarkers for accurate PJI diagnosis Periprosthetic joint infection (PJI) is one of the most severe complications after hip and knee replacement surgery. Accurate and timely diagnosis remains a clinical challenge due to limited sensitivity and specificity of current diagnostic methods. In [...]

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