microRNA biomarker of toxicity
microRNA biomarker of toxicity


microRNA biomarkers of toxicity

The term toxomiR® refers to a selection of 19 microRNAs that are enriched in various tissues. Toxicant-induced changes in the transcription and secretion of toxomiRs® are highly sensitive to toxic effects occuring in the liver, kidney, central nervous system, heart, muscle, lung, pancreas, vascular injury, and due to endocrine disruption. ToxomiRs® can be analyzed in serum or plasma.

This recently published review, gives detailed insight into the clinical utility of circulating microRNAs as biomarkers of toxicity.

€ 147.– / sample

microRNA biomarker of toxicity

€ 147.– / sample

microRNA biomarker of toxicity


The toxomiR® panel is available as in-house service from TAmiRNA

Non-invasive screening of toxic effects using serum or plasma

MicroRNAs in human biofluids for early detection of tissue injury after exposure to toxic substances

High sequence conservation makes cross-species application possible

Rapid and robust solution for quantifying toxic effects in human plasma samples

Customized service available with analysis targeted on specific set of microRNAs or tissue types

service requirements

Frozen serum or plasma sample aliquots of at least 200 μl

price list

sample number price/sample
n<=48 € 275.–
n<=96 € 194.–
n<=154 € 175.–
n<=192 € 156.–
n>192 € 147.–

frequently asked questions (FAQ)

Upon request the analysis can be targeted to a specific set of microRNAs/tissue.

The toxomiR® panel is intended to be used with human samples. However, orthologs for toxomiR® do exist in other species, allowing the use of adapted version of the Panel in non-mammalian species. To assess the feasibility of such projects, please contact us.

5 control primers to monitor assay and sample quality are included in the panel.

TAmiRNA´s toxomiR® panel has been standardized to a volume of 200 µL plasma as starting material to ensure high RNA yield and prevent inhibition of downstream PCR amplification using the Serum/Plasma RNA extraction kit. For further information read our guidelines detailing RNA purification and sample preparation for the toxomiR® kit​.

LOD: 10 copies/µl (6 replicates, 95% positive detection); LLOQ: 35 copies/µl

Intra-assay (n=6) ≤ 20%, Inter-assay (n=3) ≤ 2

microRNA biomarker of toxicity
microRNA biomarker of toxicity
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