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11 11, 2025

Distinct microRNA profiles in human amniotic membrane its vesicular and non-vesicular secretome revealed

2025-11-11T08:44:13+01:00November 11th, 2025|exosomes, extracellular vesicle, Illumina NewSeq2000, microRNA, microRNA services, miND, miND spike ins, miND spike-in, NGS, quality|0 Comments

Vienna, Austria – November 2025 TAmiRNA scientist have contributed significantly to a new study published by the Ludwig Boltzmann Institute for Traumatology, which is titled “Distinct miRNA profiles in human amniotic tissue and its vesicular and non-vesicular secretome”. The article was published in Frontiers in Cell and Developmental Biology on October 29th 2025. Human amniotic membrane (hAM) has been used in tissue regeneration and wound healing applications. In this study, the miND® small RNA-sequencing workflow was applied to generate fresh insights into the microRNA composition of two spatially and physiologically distinct regions of the human amniotic membrane (hAM) and its secreted extracellular vesicles (EVs) and protein-bound miRNAs. The work highlights how advanced analytical workflows can uncover tissue- [...]

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3 11, 2025

TAmiRNA launches the new lyophilized miND® spike-in kit for small RNA-sequencing quality control

2025-11-03T11:11:21+01:00November 3rd, 2025|miND, miND spike ins, miND spike-in, NGS, quality|0 Comments

Vienna, Austria – November 2025 TAmiRNA proudly announces the release of its miND® spike-in kit in a new lyophilized format, optimized for the preparation and analysis of 96 small RNA-sequencing libraries. This upgraded format improves handling, stability, and integration with standard small RNA-sequencing workflows, ensuring seamless compatibility with commonly used library preparation kits. The new lyophilized miND® spike-in kit combines ease of use and long-term stability with TAmiRNA’s proven spike-in design (5’ and 3’ end randomization) for accurate and reproducible normalization in small RNA-sequencing experiments. The revised 96-reaction format is ideal for medium- to large-scale studies and simplifies quality control across multiple runs. In addition, TAmiRNA has generated new data confirming the robust performance and stability of [...]

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14 10, 2025

hepatoMX Project Kickoff: TAmiRNA and You2Yourself Join Forces to Develop a Groundbreaking Urinary microRNA Diagnostic for Liver Disease

2025-10-14T08:25:31+02:00October 14th, 2025|biomarker, Biomarker Discovery, biomarkers, hepatoMX, Illumina NewSeq2000, microRNA services, microRNAs, miND, miND spike ins, NGS, sequencing, small RNA-sequencing, smallRNA|Comments Off on hepatoMX Project Kickoff: TAmiRNA and You2Yourself Join Forces to Develop a Groundbreaking Urinary microRNA Diagnostic for Liver Disease

We are excited to announce the official start of the EUREKA Eurostars project hepatoMX — a three-year collaboration between You2Yourself (Y2Y), a Dutch company specializing in small RNA-based early disease detection, and TAmiRNA GmbH, an Austrian SME with expertise in microRNA biomarker discovery and diagnostic test development (hepatomiR®). The project officially started on April 1, 2025, and aims to revolutionize the early detection of metabolic liver disease. The hepatoMX project will leverage TAmiRNA’s clinical expertise in liver diagnostics and Y2Y’s unique Urimon cohort that captures the dynamics of disease development to deliver a validated diagnostic test utilizing a proprietary urinary microRNA biomarker panel to identify early-stage liver disease in a simple and non-invasive manner. This innovative approach [...]

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9 10, 2025

Microvascular microRNA Signatures in Sepsis: A High-Resolution View

2025-10-09T10:29:18+02:00October 9th, 2025|biomarker, Biomarker Discovery, biomarkers, Illumina NewSeq2000, laser microdissection (LMD), microRNA services, microRNAs, miND, miND spike ins, NGS, sequencing, small RNA-sequencing, smallRNA|Comments Off on Microvascular microRNA Signatures in Sepsis: A High-Resolution View

Sepsis drives profound microvascular injury, particularly in the kidney. But how do microRNAs (miRNAs) - the small regulators of gene expression - respond within distinct vascular compartments during this insult? A new study by Luxen et al.  published in Scientific Reports on October 2nd 2025 takes on this question using a clever methodological combination: laser microdissection (LMD) of microvascular subregions (arterioles, glomeruli, capillaries, postcapillary venules) followed by small RNA sequencing using TAmiRNA´s miND® workflow for highly sensitive and quantitative microRNA analysis. Why this approach matters Traditional microRNA profiling of whole tissues obscures spatial heterogeneity. With LMD, the authors could precisely isolate defined microvascular zones from kidney sections. Even with the tiny RNA yields from these isolated compartments, [...]

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22 09, 2025

TAmiRNA @ GSEV 2025

2025-09-22T08:52:59+02:00September 22nd, 2025|biomarker, Biomarker Discovery, biomarkers, microRNAs, NGS, periprosthetic joint infections, small RNA-sequencing, Synovial fluid|Comments Off on TAmiRNA @ GSEV 2025

TAmiRNA Announces Gold Sponsorship of GSEV Autumn Meeting 2025 and Presentation by Matthias Hackl TAmiRNA, a pioneer in transcriptomics-based biomarker research, is proud to announce its participation as a Gold Sponsor at the GSEV Autumn Meeting 2025, hosted by the German Society for Extracellular Vesicles (GSEV). The annual conference will take place on September 25–26, 2025, at the Audimax of the University Hospital Essen. As part of the scientific program, Matthias Hackl (TAmiRNA) will deliver a presentation on Thursday, September 25, at 12:15 pm entitled: “Small RNA-sequencing (miND®) Enables Discovery of EV-specific MicroRNA Signatures to Support EV Therapeutics Development.” “Using miND®, we can robustly identify EV-specific microRNA signatures – a critical step toward enabling data-driven research and [...]

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8 09, 2025

TAmiRNA @ EBJIS 2025

2025-09-17T11:35:44+02:00September 8th, 2025|biomarker, Biomarker Discovery, biomarkers, microRNAs, NGS, periprosthetic joint infections, small RNA-sequencing, Synovial fluid|Comments Off on TAmiRNA @ EBJIS 2025

TAmiRNA is proud to announce its participation at the upcoming European Bone and Joint Infection Society (EBJIS) Meeting 2025 in Ferrara, Italy. On Thursday, September 11, 2025 at 11:00 (Sala Emilia), Dr. Bernhard JH Frank will present groundbreaking new results from a collaborative study conducted with the Orthopaedic Hospital Speising and Dr. Jochen G. Hofstätter. The presentation is entitled: “Synovial fluid microRNA biomarkers enable accurate diagnosis of hip and knee periprosthetic joint infections.” Synovial fluid microRNA biomarkers for accurate PJI diagnosis Periprosthetic joint infection (PJI) is one of the most severe complications after hip and knee replacement surgery. Accurate and timely diagnosis remains a clinical challenge due to limited sensitivity and specificity of current diagnostic methods. In [...]

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16 07, 2025

Webinar Announcement

2025-07-16T10:01:30+02:00July 16th, 2025|biomarker, Biomarker Discovery, biomarkers, FFPE, microRNAs, miND spike-in, NGS, small RNA-sequencing|Comments Off on Webinar Announcement

🔬 Join us For Our Upcoming Webinar with BioEcho Life Sciences In this session, we'll explore: Discover how TAmiRNA’s miND® small RNA-sequencing assay enables absolute quantification and quality control through synthetic spike-ins, making it a powerful tool for transcriptomic profiling in challenging samples. Learn about the BioEcho EchoLUTION FFPE RNA extraction kit, which preserves the integrity of small and large RNAs to maximize sensitivity and reproducibility in FFPE tissue analysis. See case studies demonstrating how integrated workflows—from RNA extraction to sequencing and bioinformatic analysis—support microRNA biomarker identification and mechanistic insights. Explore bioinformatic tools for analyzing small RNA-seq and multiomic datasets to uncover microRNA function, cellular origin, and regulatory networks. Whether you are working with archived tissue samples or liquid biopsies, [...]

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26 06, 2025

Unlocking the Next Generation of Biomarkers: Introducing TAmiRNA’s New circRNA Analysis Service

2025-06-26T15:23:19+02:00June 26th, 2025|biomarker, Biomarker Discovery, biomarkers, circRNA analysis service, liquid biopsies, microRNAs, NGS, small RNA-sequencing|Comments Off on Unlocking the Next Generation of Biomarkers: Introducing TAmiRNA’s New circRNA Analysis Service

The world of non-coding RNAs is continually expanding, revealing new layers of biological complexity and therapeutic potential. Among the most exciting discoveries are circular RNAs (circRNAs). Unlike their linear counterparts, circRNAs form covalently closed loops, granting them remarkable stability and unique functions in gene regulation. This intrinsic stability, coupled with their presence in biofluids, positions circRNAs as powerful new candidates for biomarker discovery and novel therapeutic targets. The Challenge of CircRNA Analysis from Biofluids Despite their immense promise, accurately isolating and quantifying circRNAs, especially from challenging biofluid samples like plasma and serum, has presented significant technical hurdles. These samples typically contain very low concentrations of circRNAs alongside a vast excess of highly abundant linear RNAs (like ribosomal [...]

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8 05, 2025

Transcriptomics Webinar Announcement

2025-05-08T10:42:15+02:00May 8th, 2025|biomarker, Biomarker Discovery, biomarkers, microRNAs, NGS, small RNA-sequencing|Comments Off on Transcriptomics Webinar Announcement

🔬 Join us for an insightful transcriptomics webinar where we will delve into cutting-edge strategies for biomarker discovery, basic research, and translational applications. Whether you're focused on diagnostics or overcoming the challenges of low-input sample analysis, this webinar is designed for you! Title: Harnessing Transcriptomics: microRNA and mRNA analysis for Biomarker Discovery, Basic Research, and Translational Applications What to Expect: Comprehensive Transcriptomics Sequencing Services tailored to your research needs Insights into Biomarker Discovery, driving breakthrough advancements in diagnostics Strategies to overcome challenges with low-input samples, including biofluids and extracellular vesicles Opportunity to connect with our experts to discuss your transcriptomics goals and potential collaborations 📅 Date: 28.05.2025 🕒 Time: 13:00 -14:00 CET Presentation by Matthias Hackl, TAmiRNA GmbH [...]

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9 01, 2025

TAmiRNA ‘2024 In Review’

2025-01-09T14:05:02+01:00January 9th, 2025|biomarker, Biomarker Discovery, biomarkers, CE-IVD, congress, EVscale, exosomes, extracellular vesicle, hepatomiR kit, Illumina NewSeq2000, ISO 13485, liquid biopsies, Liver disease, microRNA, microRNA services, microRNAs, NGS, PCR testing service, quality, sequencing, small RNA-sequencing, smallRNA, test service|Comments Off on TAmiRNA ‘2024 In Review’

2024: A Year of Growth, Innovation, and Collaboration 2024 has come to a close. We are proud to reflect on the milestones and achievements we’ve reached together with our incredible team, customers, partners, and supporters. Here’s a look back at what we accomplished this year: 👩‍🔬 Team Expansion Welcomed 3 talented new members to our growing team. 🏥 Diagnostic Implementation Successfully rolled out our CE-IVD microRNA liver function test in 5+ clinics, advancing molecular diagnostics. ✅ Service Excellence Completed over 80 RNA service projects, achieving 100% customer satisfaction. 🛠 Bioinformatics Innovation Developed 2 new pipelines: isomiR analysis and tRNA analysis, enhancing our capabilities. 🧬 Expanded Service Offerings Added whole-transcriptome sequencing for mRNA, lncRNA, and circRNA in liquid biopsies to our service portfolio. [...]

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