sequencing Archives - Tamirna - stability for life

22 10, 2026

Our microRNA toolbox has a new look
Our microRNA toolbox has a new look

biomarker, diagnostics, NGS, sequencing, small RNA-sequencing, smallRNA

Our microRNA toolbox has a new look

2026-10-22T11:40:00+02:00October 22nd, 2026|biomarker, diagnostics, NGS, sequencing, small RNA-sequencing, smallRNA|0 Comments

Anyone working with microRNAs knows the problem: there are a lot of databases and analysis tools, and it isn’t always obvious which one fits your research question. Plus, every year new tools are released that facilitate the functional analysis of microRNAs. That’s why we reworked our overview of web-based microRNA tools. It is now live with a new design. The biggest change is the structure. Instead of a simple list, the tools are now grouped by common research questions. These cover target prediction, experimentally validated miRNA-mRNA target interactions, pathway analysis, sequence and nomenclature, tissue expression, disease associations, small RNA-seq data analysis and data visualisation. This takes you straight from your question to the right tool. The page [...]

21 01, 2026

New white paper with RoosterBio on omics-tools for EV characterization
New white paper with RoosterBio on omics-tools for EV characterization

EV characterization, exosomes, extracellular vesicle, miND, miND spike-in, NGS, sequencing, small RNA-sequencing

New white paper with RoosterBio on omics-tools for EV characterization

2026-01-22T11:53:45+01:00January 21st, 2026|EV characterization, exosomes, extracellular vesicle, miND, miND spike-in, NGS, sequencing, small RNA-sequencing|Comments Off on New white paper with RoosterBio on omics-tools for EV characterization

In this white paper, TAmiRNA and RoosterBio present a comprehensive small RNA-sequencing–based characterization of mesenchymal stem cell (MSC)–derived exosomes produced using RoosterBio’s standardized, xeno-free manufacturing platform. The study was designed to assess both the analytical robustness of TAmiRNA’s miND® small RNA-sequencing workflow and the biological relevance of microRNA cargo profiling as an advanced “omics-based” characterization strategy for therapeutic extracellular vesicles (EVs). Using technical replicates and independent EV vials, we demonstrate that small RNA-sequencing performed with the miND® workflow yields highly reproducible and quantitatively consistent microRNA profiles, confirming the robustness of the analytical pipeline and the stability of RoosterBio’s EV products. In addition, comparative profiling of EVs derived from umbilical cord, bone marrow, and adipose tissue MSCs revealed [...]

14 10, 2025

hepatoMX Project Kickoff: TAmiRNA and You2Yourself Join Forces to Develop a Groundbreaking Urinary microRNA Diagnostic for Liver Disease
hepatoMX Project Kickoff: TAmiRNA and You2Yourself Join Forces to Develop a Groundbreaking Urinary microRNA Diagnostic for Liver Disease

biomarker, Biomarker Discovery, biomarkers, hepatoMX, Illumina NewSeq2000, microRNA services, microRNAs, miND, miND spike ins, NGS, sequencing, small RNA-sequencing, smallRNA

hepatoMX Project Kickoff: TAmiRNA and You2Yourself Join Forces to Develop a Groundbreaking Urinary microRNA Diagnostic for Liver Disease

2025-10-14T08:25:31+02:00October 14th, 2025|biomarker, Biomarker Discovery, biomarkers, hepatoMX, Illumina NewSeq2000, microRNA services, microRNAs, miND, miND spike ins, NGS, sequencing, small RNA-sequencing, smallRNA|Comments Off on hepatoMX Project Kickoff: TAmiRNA and You2Yourself Join Forces to Develop a Groundbreaking Urinary microRNA Diagnostic for Liver Disease

We are excited to announce the official start of the EUREKA Eurostars project hepatoMX — a three-year collaboration between You2Yourself (Y2Y), a Dutch company specializing in small RNA-based early disease detection, and TAmiRNA GmbH, an Austrian SME with expertise in microRNA biomarker discovery and diagnostic test development (hepatomiR®). The project officially started on April 1, 2025, and aims to revolutionize the early detection of metabolic liver disease. The hepatoMX project will leverage TAmiRNA’s clinical expertise in liver diagnostics and Y2Y’s unique Urimon cohort that captures the dynamics of disease development to deliver a validated diagnostic test utilizing a proprietary urinary microRNA biomarker panel to identify early-stage liver disease in a simple and non-invasive manner. This innovative approach [...]

9 10, 2025

Microvascular microRNA Signatures in Sepsis: A High-Resolution View
Microvascular microRNA Signatures in Sepsis: A High-Resolution View

biomarker, Biomarker Discovery, biomarkers, Illumina NewSeq2000, laser microdissection (LMD), microRNA services, microRNAs, miND, miND spike ins, NGS, sequencing, small RNA-sequencing, smallRNA

Microvascular microRNA Signatures in Sepsis: A High-Resolution View

2025-10-09T10:29:18+02:00October 9th, 2025|biomarker, Biomarker Discovery, biomarkers, Illumina NewSeq2000, laser microdissection (LMD), microRNA services, microRNAs, miND, miND spike ins, NGS, sequencing, small RNA-sequencing, smallRNA|Comments Off on Microvascular microRNA Signatures in Sepsis: A High-Resolution View

Sepsis drives profound microvascular injury, particularly in the kidney. But how do microRNAs (miRNAs) - the small regulators of gene expression - respond within distinct vascular compartments during this insult? A new study by Luxen et al. published in Scientific Reports on October 2nd 2025 takes on this question using a clever methodological combination: laser microdissection (LMD) of microvascular subregions (arterioles, glomeruli, capillaries, postcapillary venules) followed by small RNA sequencing using TAmiRNA´s miND® workflow for highly sensitive and quantitative microRNA analysis. Why this approach matters Traditional microRNA profiling of whole tissues obscures spatial heterogeneity. With LMD, the authors could precisely isolate defined microvascular zones from kidney sections. Even with the tiny RNA yields from these isolated compartments, [...]

5 02, 2025

7Bioscience and TAmiRNA collaborate to expand access to our cutting-edge transcriptomics services
7Bioscience and TAmiRNA collaborate to expand access to our cutting-edge transcriptomics services

biomarker, biomarkers, microRNA services, microRNAs, sequencing, smallRNA

7Bioscience and TAmiRNA collaborate to expand access to our cutting-edge transcriptomics services

2025-02-04T11:11:02+01:00February 5th, 2025|biomarker, biomarkers, microRNA services, microRNAs, sequencing, smallRNA|Comments Off on 7Bioscience and TAmiRNA collaborate to expand access to our cutting-edge transcriptomics services

We are delighted to welcome 7Bioscience as the new distribution partner of TAmiRNA GmbH! With a strong track record in clinical and research molecular biology, 7Bioscience will support to offer TAmiRNA’s innovative service solutions to a broader audience. This partnership will enhance accessibility to our cutting-edge transcriptomics analysis. We look forward to a successful collaboration with 7Bioscience and the opportunities this partnership will bring!

9 01, 2025

TAmiRNA ‘2024 In Review’

2025-01-09T14:05:02+01:00January 9th, 2025|biomarker, Biomarker Discovery, biomarkers, CE-IVD, congress, EVscale, exosomes, extracellular vesicle, hepatomiR kit, Illumina NewSeq2000, ISO 13485, liquid biopsies, Liver disease, microRNA, microRNA services, microRNAs, NGS, PCR testing service, quality, sequencing, small RNA-sequencing, smallRNA, test service|Comments Off on TAmiRNA ‘2024 In Review’

2024: A Year of Growth, Innovation, and Collaboration 2024 has come to a close. We are proud to reflect on the milestones and achievements we’ve reached together with our incredible team, customers, partners, and supporters. Here’s a look back at what we accomplished this year: 👩‍🔬 Team Expansion Welcomed 3 talented new members to our growing team. 🏥 Diagnostic Implementation Successfully rolled out our CE-IVD microRNA liver function test in 5+ clinics, advancing molecular diagnostics. ✅ Service Excellence Completed over 80 RNA service projects, achieving 100% customer satisfaction. 🛠 Bioinformatics Innovation Developed 2 new pipelines: isomiR analysis and tRNA analysis, enhancing our capabilities. 🧬 Expanded Service Offerings Added whole-transcriptome sequencing for mRNA, lncRNA, and circRNA in liquid biopsies to our service portfolio. [...]

15 10, 2024

Eager to lern more about differential miRNA expression patterns in Type 2 diabetes mellitus
Eager to lern more about differential miRNA expression patterns in Type 2 diabetes mellitus

biomarker, bone diseases, bone fracture risk assessment, diabetes, microRNA services, microRNAs, miND spike ins, NGS, sequencing, smallRNA

Eager to lern more about differential miRNA expression patterns in Type 2 diabetes mellitus

2026-06-29T08:16:40+02:00October 15th, 2024|biomarker, bone diseases, bone fracture risk assessment, diabetes, microRNA services, microRNAs, miND spike ins, NGS, sequencing, smallRNA|Comments Off on Eager to lern more about differential miRNA expression patterns in Type 2 diabetes mellitus

Excited to share our latest study on the link between Type 2 Diabetes Mellitus (T2DM) and bone fragility using miRNA profiling in a polygenic mouse model! 🧬🦴 🔍 Research Highlights: We utilized an unbiased genome-wide approach to identify dysregulated miRNAs in serum, bone marrow, and bone of the TallyHo/JngJ (TH) mouse model, which closely mirrors T2DM in humans. Key findings include upregulation of miRNAs such as mmu-miR-466i-5p and mmu-miR-1195 in both serum and bone marrow of diabetic mice. Dysregulated miRNAs were linked to pathways associated with diabetes-related signaling and diabetic bone disease, shedding light on potential mechanistic pathways. Cell-type enrichment analysis pointed towards miRNAs enriched in specific cell types like immune cells, hepatocytes, and mesenchymal stem cells, [...]

18 09, 2024

Eager to lern more about neuron-derived extracellular vesicles as predictive biomarkers
Eager to lern more about neuron-derived extracellular vesicles as predictive biomarkers

biomarker, biomarkers, exosomes, microRNA services, microRNAs, miND spike ins, NGS, sequencing, smallRNA

Eager to lern more about neuron-derived extracellular vesicles as predictive biomarkers

2024-09-18T14:10:09+02:00September 18th, 2024|biomarker, biomarkers, exosomes, microRNA services, microRNAs, miND spike ins, NGS, sequencing, smallRNA|Comments Off on Eager to lern more about neuron-derived extracellular vesicles as predictive biomarkers

A new study from the University of Trieste explores the potential of microRNA (miRNA) profiles in neuron-derived extracellular vesicles (NDEVs) as predictive biomarkers for adverse drug reactions (ADRs) in children receiving ketamine. This research, leveraging TAmiRNA's Next-Generation Sequencing (NGS)-based miND® pipeline, identified specific miRNAs (miR-18a-3p, miR-484, and miR-548az-5p) as potential tools to predict ketamine-induced ADRs. This breakthrough not only advances our understanding of ketamine's side effects in children but also demonstrates the biomarker potential of organ-specific EVs and their miRNA cargo. Interested in our of extracellular vesicles (EVs) and exosomes services - click here! click here to read the paper

9 08, 2024

Eager to lern more about Early Detection of Colorectal Cancer through MicroRNA Profiling
Eager to lern more about Early Detection of Colorectal Cancer through MicroRNA Profiling

biomarker, biomarkers, exosomes, microRNA services, microRNAs, miND spike ins, NGS, sequencing, smallRNA

Eager to lern more about Early Detection of Colorectal Cancer through MicroRNA Profiling

2024-08-09T11:17:20+02:00August 9th, 2024|biomarker, biomarkers, exosomes, microRNA services, microRNAs, miND spike ins, NGS, sequencing, smallRNA|Comments Off on Eager to lern more about Early Detection of Colorectal Cancer through MicroRNA Profiling

TAmiRNA and its partner Biomedica are proud to announce that researchers from the Jagiellonian University Medical College used our innovative small RNA-sequencing pipeline (miND®) to unravel novel miRNA expression profiles in colorectal cancer cell lines and the extracellular vesicles (EVs) they produce. Colorectal cancer ranks as the third most common cancer in men and the second in women globally. Late diagnosis significantly contributes to rising morbidity and mortality rates, emphasizing the urgent need for new markers for early and precise detection. The analysis of miRNAs in plasma-derived EVs and tumor samples from CRC patients revealed a similar miRNA expression profile between patient samples and CRC cell lines. Importantly, miR-182-5p, miR-196b-5p, miR-425-5p, and miR-429 were found regulated in [...]

3 06, 2024

LEPTON and TAmiRNA collaborate on microRNA immune therapy discovery
LEPTON and TAmiRNA collaborate on microRNA immune therapy discovery

biomarker, biomarkers, microRNA services, microRNAs, sequencing, smallRNA

LEPTON and TAmiRNA collaborate on microRNA immune therapy discovery

2024-06-03T10:16:12+02:00June 3rd, 2024|biomarker, biomarkers, microRNA services, microRNAs, sequencing, smallRNA|Comments Off on LEPTON and TAmiRNA collaborate on microRNA immune therapy discovery

Lepton Pharmaceuticals LTD (Lepton), a biopharmaceutical company, focused on discovery and development of novel treatments for unmet medical needs, exploiting the subtle silencing of coding RNA expression by noncoding RNA molecules microRNA (miRNA) and small interfering RNA, and TAmiRNA GmbH, a research and development company specialized in the discovery and validation of microRNA biomarkers to improve patients’ life, announce the reinforcement of their collaboration by signing a second agreement to discover the epigenetic pathways that affect the activity of microRNAs thereby improving genetically modified immune cells therapy. Lepton together with Freiburg University is developing a technology (the Castling Technology) for enhancement of immune cells (T-cells or CAR T-cells, B-cells, natural killer (NK) cells, T-regulatory cells, macrophages, stem cells [...]