Eager to lern more about Sepsis-associated acute kidney injury?
We are pleased to share our latest publication, a collaborative effort with TAmiRNA, titled 'Sepsis-Induced Heterogeneous Transcription of Coagulation- and Inflammation-Associated Genes in Renal Microvasculature,' which has been published in Thrombosis Research. Through the integration of TAmiRNA's high-sensitivity gene expression profiling techniques (RT-qPCR and smallRNAseq/RNAseq) and the advanced laser microdissection technology from Dutch company Vivomicx, our study unveils the diverse transcriptional responses of microvascular compartments to sepsis-associated acute kidney injury (SA-AKI). Our findings demonstrate that distinct changes occur in the expression of coagulation- and inflammation-related genes across microvascular compartments in response to SA-AKI. This heterogeneity underscores the complexity of the microvascular response to sepsis and highlights potential avenues for targeted therapeutic intervention. Moving forward, our research will [...]
