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6 09, 2024

TAmiRNA at EUROTOX 2024 in Copenhagen

2024-09-11T08:35:27+02:00September 6th, 2024|biomarker, biomarkers, drug-induced pancreatic injury, microRNAs, miND, miND spike ins, NGS, small RNA-sequencing, TransBioLine|Comments Off on TAmiRNA at EUROTOX 2024 in Copenhagen

On September 10, our CEO & CSO, Dr. Matthias Hackl, will discuss “Small RNA-sequencing based discovery of microRNAs for CNS-injury biomarkers” during the EUROTOX Short Orals Session. He’ll highlight the efforts of TAmiRNA and the IMI consortium TransBioLine in advancing microRNAs as biomarkers of drug-induced brain injury. TAmiRNA will also bring a poster (P06-01) to the conference, authored by Senior Scientist, Dr. Kseniya Khamina-Kotisch, on “NGS-based discovery of microRNA biomarkers of drug-induced pancreatic injury (DIPI),” showcasing the merits of small RNA-sequencing (miND) for biomarker discovery. Don’t miss this opportunity to explore TAmiRNA's latest advancements in microRNA diagnostics. Reach out to Matthias directly to meet and discuss our latest developments and how TAmiRNA's  services can assist your business! TAmiRNA [...]

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2 09, 2024

TAmiRNA at SSCC/SGK in Zürich

2024-09-11T08:36:01+02:00September 2nd, 2024|biomarker, biomarkers, exosomes, extracellular vesicle, microRNAs, miND spike ins, NGS|Comments Off on TAmiRNA at SSCC/SGK in Zürich

TAmiRNA will spotlight its miND® NextGen small RNA-sequencing platform and the hepatomiR® test—Europe's first CE-IVD marked test for liver function microRNA biomarkers—at the Zürich conference. These innovations highlight TAmiRNA's strengths in microRNA diagnostic development. Dr. Matthias Hackl, CEO and Chief Scientific Officer, will present "MicroRNAs as a Novel Class of Biomarkers" on Friday, September 6, in Session 6: New Technologies. He will discuss the critical role of miRNA biomarkers and TAmiRNA's advanced sequencing techniques, which speed up the discovery of novel biomarker associations. Don’t miss this opportunity to explore TAmiRNA's latest advancements in microRNA diagnostics. Reach out to Matthias directly to meet and discuss our latest developments and how TAmiRNA's  services can assist your business! TAmiRNA [...]

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9 08, 2024

Eager to lern more about Early Detection of Colorectal Cancer through MicroRNA Profiling

2024-08-09T11:17:20+02:00August 9th, 2024|biomarker, biomarkers, exosomes, microRNA services, microRNAs, miND spike ins, NGS, sequencing, smallRNA|Comments Off on Eager to lern more about Early Detection of Colorectal Cancer through MicroRNA Profiling

TAmiRNA and its partner Biomedica are proud to announce that researchers from the Jagiellonian University Medical College used our innovative small RNA-sequencing pipeline (miND®) to unravel novel miRNA expression profiles in colorectal cancer cell lines and the extracellular vesicles (EVs) they produce. Colorectal cancer ranks as the third most common cancer in men and the second in women globally. Late diagnosis significantly contributes to rising morbidity and mortality rates, emphasizing the urgent need for new markers for early and precise detection. The analysis of miRNAs in plasma-derived EVs and tumor samples from CRC patients revealed a similar miRNA expression profile between patient samples and CRC cell lines. Importantly, miR-182-5p, miR-196b-5p, miR-425-5p, and miR-429 were found regulated in [...]

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18 06, 2024

TAmiRNA at SelectBIO Congress Rotterdam

2024-09-11T08:36:38+02:00June 18th, 2024|biomarker, biomarkers, exosomes, extracellular vesicle, microRNAs, miND spike ins, NGS|Comments Off on TAmiRNA at SelectBIO Congress Rotterdam

TAmiRNA CEO/CSO Matthias Hackl and scientst Marianne Pultar will attend the SelectBIO Congress Rotterdam next week and will showcase its services at Booth E5 in the Exhibition Zone at the Hilton Rotterdam. TAmiRNA will also be a scientific contributor to the conference with a poster presentation on how to leverage extracellular vesicle microRNA cargo to enable in-vivo tracing of EVs based on their unique cargoes (biodistribution). Reach out to Matthias and Marianne directly to meet and discuss our latest developments and how TAmiRNA's  services can assist your business! TAmiRNA CEO Dr. Matthias Hackl

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3 06, 2024

LEPTON and TAmiRNA collaborate on microRNA immune therapy discovery

2024-06-03T10:16:12+02:00June 3rd, 2024|biomarker, biomarkers, microRNA services, microRNAs, sequencing, smallRNA|Comments Off on LEPTON and TAmiRNA collaborate on microRNA immune therapy discovery

Lepton Pharmaceuticals LTD (Lepton), a biopharmaceutical company, focused on discovery and development of novel treatments for unmet medical needs, exploiting the subtle silencing of coding RNA expression by noncoding RNA molecules microRNA (miRNA) and small interfering RNA, and TAmiRNA GmbH, a research and development company specialized in the discovery and validation of microRNA biomarkers to improve patients’ life, announce the reinforcement of their collaboration by signing a second agreement to discover the epigenetic pathways that affect the activity of microRNAs thereby improving genetically modified immune cells therapy. Lepton together with Freiburg University is developing a technology (the Castling Technology) for enhancement of immune cells (T-cells or CAR T-cells, B-cells, natural killer (NK) cells, T-regulatory cells, macrophages, stem cells [...]

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24 04, 2024

EVscale™ platform

2024-06-14T08:13:58+02:00April 24th, 2024|biomarker, Evercyte, exosomes, extracellular vesicle, microRNA services, microRNAs, miND spike ins, NGS, Phoenestra, sequencing, smallRNA|Comments Off on EVscale™ platform

The EVscale™ platform, developed by Evercyte, Phoenestra, and TAmiRNA, offers a comprehensive solution for pharmaceutical and biotech manufacturers requiring exosomes and EVs at commercial scale. Drawing on the combined expertise of the three partners, EVscale™ provides customizable projects, including specific cell sourcing, EV characterization, scalable manufacturing, and linking EV biological functions to RNA and protein EV components. EVscale™ advantages: Offers a fundamental advantage over conventional sourcing of therapeutic exosomes from primary cells, eliminating donor-to-donor variability and other issues like scaling difficulties, variable process performance, inconsistent batch quality, and under-developed downstream processing technologies. Provides a unique one-stop-shop offer, allowing customers to tailor end-product parameters based on their project’s specific needs. By combining miRNomics with transcriptomic and proteomic analyses, [...]

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10 04, 2024

Eager to lern more about Sepsis-associated acute kidney injury?

2024-04-10T13:16:00+02:00April 10th, 2024|biomarker, biomarkers, microRNA services, microRNAs, microstructure, miND spike ins, NGS, sequencing, smallRNA, Vivomicx|Comments Off on Eager to lern more about Sepsis-associated acute kidney injury?

We are pleased to share our latest publication, a collaborative effort with TAmiRNA, titled 'Sepsis-Induced Heterogeneous Transcription of Coagulation- and Inflammation-Associated Genes in Renal Microvasculature,' which has been published in Thrombosis Research. Through the integration of TAmiRNA's high-sensitivity gene expression profiling techniques (RT-qPCR and smallRNAseq/RNAseq) and the advanced laser microdissection technology from Dutch company Vivomicx, our study unveils the diverse transcriptional responses of microvascular compartments to sepsis-associated acute kidney injury (SA-AKI). Our findings demonstrate that distinct changes occur in the expression of coagulation- and inflammation-related genes across microvascular compartments in response to SA-AKI. This heterogeneity underscores the complexity of the microvascular response to sepsis and highlights potential avenues for targeted therapeutic intervention. Moving forward, our research will [...]

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4 04, 2024

Exciting news!

2024-04-04T13:16:30+02:00April 4th, 2024|biomarker, biomarkers, Illumina NewSeq2000, microRNA services, microRNAs, miND spike ins, NGS, sequencing, smallRNA|Comments Off on Exciting news!

We just received the Illumina NextSeq 2000 machine, marking a significant milestone in our journey towards cutting-edge research and innovation. This powerful instrument will drive our NGS services and allow us to deliver results quicker than ever before.

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5 03, 2024

TAmiRNA at RNA Leaders conference in Basel

2024-03-05T08:19:26+01:00March 5th, 2024|biomarker, biomarkers, microRNAs, NGS|Comments Off on TAmiRNA at RNA Leaders conference in Basel

TAmiRNA CEO/CSO Matthias Hackl will attend the RNA Leaders conference in Basel next week to speak about the recent development of reliable miRNA safety biomarkers and their potential to indicate injury of the liver, kidneys, pancreas, blood vessels, and central nervous system for drug development purposes. Reach out to Matthias directly to meet with him before or after his presentation on Wednesday, March 13th at 12:25 pm and discuss our latest developments and how TAmiRNA's  services can assist your business!

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13 02, 2024

Webinar – COST Action AtheroNET

2024-02-13T11:20:12+01:00February 13th, 2024|biomarker, biomarkers, exosomes, extracellular vesicle, microRNA, microRNA services, microRNAs, quality, sequencing, smallRNA|Comments Off on Webinar – COST Action AtheroNET

Looking forward to sharing our insights from 10+ years of extracellular microRNA (and recently long RNA as well) biomarker discovery and diagnostic test development with the COST Action AtheroNET group. Date: 19.02.2024 Time: 19:30 CET Registration Link: https://lnkd.in/dVDDYKcA Reach out to Matthias directly after his webinar and discuss our latest developments and how TAmiRNA’s  miND spike ins and small RNA sequencing service can assist your business!

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